Biomachineries

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Chinese Wisdom:
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Under heaven, nothing is more soft and yielding than water, yet, for attacking the solid and the strong, nothing is better, it has no equal.
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Nature has designed remarkable micro/nano scale machineries through billions of years of evolution. The nanomotor of a bacterium is ~50nm in size, it is able to drive a 10mm length flagellum at about 300 turns per seconds. The embryonic fruit fly heart tube is ~ 100 mm in length, and yet it appears to be a perfect functional microfluidic pump.  How does nature achieve such remarkable feats? What are the nature's designing principles? These are a few questions that we are interested in answering.

Drosophila tube heart dynamics (Tom Sato and Wu)

In collaboration with Tom Sato at Cornell Weill Medical College, we have started exploring the relation of protein network and the cardiac pumping of embryonic fruit fly. The premise of this research is  to use the fruit fly heart as a model system to study a number of health related problems, such as cardiac arrhythmia using a combination of experiments and numerical simulations.

Shown here is a movie of beating embryonic fruit fly heart tube (click here for a larger version).  

Biofluidics Lab, 328 Duffield Hall Cornell University, Ithaca, NY 14853
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