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Biofluidics Lab, 328 Duffield Hall Cornell University, Ithaca, NY 14853 |
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A hydrogel-based microfluidic device for the studies of directed cell migration (Eugene Kalinin, Max Wasserman) We have developed a hydrogel-based microfluidic device that is capable of generating a steady and long term linear chemical concentration gradient with no through flow in a microfluidic channel. READ MORE. |
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Directing neural stem cells using a microchemotaxis device (Daniel Rhoads, Donald Lee, and Kevin Wong)Engraftment of neural stem cells (NSCs) to replace central nervous system cells lost to injury or disease is a promising treatment strategy. However, many regions of the adult brain shown low levels of permissiveness to NSC migration, limiting the effectiveness of both endogenous and transplanted NSC therapies. By enhancing the motility of the ‘stem cell pool’ to the site of central nervous system(CNS) injury or disease using chemical cues, treatment strategies will become more successful. READ MORE. |
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Who is the winner? – Probing the potency of multiple chemoattractant in Escherichia coli (Eugene Kalinin)By flowing the two side channels of our microchemotaxis device with different chemicals one can establish and maintain two independent gradients of different chemicals in the center channel. Chemotactic responses of E. coli to these "competing concentration gradients" provide clues on the comparative roles of the receptors in the cells’ chemotactic behavior. READ MORE. |
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